The Grand Highlander has a standard Secondary Collision Brake, which automatically applies the brakes in the event of a crash to help prevent secondary collisions and prevent further injuries. The Outlander doesn’t offer a post collision braking system: in the event of a collision that triggers the airbags, more collisions are possible without the protection of airbags that may have already deployed.
Both the Grand Highlander and Outlander have Rear Cross Traffic Alert, but the Grand Highlander Limited/Platinum has Parking Support Brake (automatically applies the brakes) to better prevent a collision when backing near traffic. The Outlander’s Rear Cross Traffic Alert doesn’t automatically brake.
Both the Grand Highlander and the Outlander have standard driver and passenger frontal airbags, front side-impact airbags, driver knee airbags, side-impact head airbags, front and rear seatbelt pretensioners, front wheel drive, height adjustable front shoulder belts, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, lane departure warning systems, blind spot warning systems, rearview cameras, rear cross-path warning, driver alert monitors, available all wheel drive and around view monitors.
The Toyota Grand Highlander weighs 497 to 1327 pounds more than the Mitsubishi Outlander. The NHTSA advises that heavier vehicles are much safer in collisions than their significantly lighter counterparts.

